What are the advantages of EYE Endran?

• While patents for competitor products have recently expired and PN skin boosters with the same ingredients are emerging, Eye Kkeutjuran is identical to ReXran Original in terms of PN content and efficacy. It also contains the same salmon-derived PN ingredient. It is also reasonably priced, making it a suitable option for ongoing management. PN extracted from trout or other fish is unlikely to be 100% identical to ReXran, so please ensure it is sourced from salmon.
• Unlike typical procedures, customized 'embo' treatment by adjusting skin layer depth according to the desired area, not only under the eyes but also on the eyelids and directly next to the eyes.
• Direct injection of 2cc of pure PN, without saline dilution.
• Low viscosity results in less pain and relatively faster absorption of the 'embo' phenomenon.
• Designed specifically for the eye area, allowing stable treatment even on sensitive skin.
• Less painful than general Kkeutjuran, allowing full-face treatment and improving dullness, inner dryness, and fine wrinkles.
• Due to the director's expertise in herbal acupuncture and injections, precise injection into the dermis is possible, and the 'embo' phenomenon around the eyes is confirmed directly with the patient.

What is EYE Endran (PN) Skin Booster?

EYE Endran is a skin booster containing PN (Polynucleotide) specifically formulated for the delicate skin around the eyes,

It is a precise treatment used to effectively improve fine wrinkles, dark circles, and inner dryness around the eyes.

It contains the same PN ingredient and concentration as the existing ReXran Healer, but it is specifically designed for the thin skin around the eyes, offering a smoother injection sensation, relatively less pain, and a less noticeable 'embo' phenomenon.

Why is EYE Endran necessary for the eye area?

The skin around the eyes is the thinnest and most sensitive layer on the face.

Because it is thin, it is sensitive to external stimuli, and signs of aging and dryness appear quickly in this area.

In particular, the skin barrier is prone to breakdown, often leading to inner dryness, fine wrinkles, and bluish dark circles appearing simultaneously.

However, structurally, this area has little subcutaneous fat and a thin dermal layer, limiting the effectiveness of moisturizers or eye creams.

This is why precisely injecting PN into the dermal layer to induce regeneration is an effective method.

What is PN (Polynucleotide)?

PN is a high-purity biomaterial derived from salmon DNA.

Compared to the commonly known PDRN, it has a larger molecular weight and higher efficacy duration and ability to induce dermal layer reactions.

Simply put, while PDRN helps with basic moisturizing and regeneration, PN directly stimulates the dermal layer to bring about structural changes.

PN promotes skin improvement through the following processes:

Stimulates fibroblasts to produce collagen and elastin → gives skin elasticity, reduces fine wrinkles, and makes the skin surface smooth and firm.

Increases secretion of growth factors such as TGF, FGF, VEGF → promotes skin recovery and rapidly aids the regeneration of damaged tissues. It also alleviates inflammatory responses and maintains healthy skin.

Induces regeneration of epidermal cells and strengthens the skin barrier → strengthens the connections between keratinocytes and prevents moisture loss, improving inner dryness.

The skin has a barrier structure composed of bricks (keratinocytes) and cement (intercellular lipids),

PN helps restore this cement function, suppressing moisture evaporation and simultaneously improving inner dryness and sensitivity.

Repairs damaged dermal tissue and increases thickness → thickens the thinned dermis, contributing to dark circle reduction and fine wrinkle improvement.

The skin has a barrier structure composed of bricks (keratinocytes) and cement (intercellular lipids). PN helps restore this cement function, suppressing moisture evaporation and simultaneously improving inner dryness and sensitivity.

The 'Embo' Phenomenon and the Importance of Dermal Layer Injection

Because the dermal layer is structurally narrow,

when the drug is injected, a swelling phenomenon occurs.

This is called the 'embo' phenomenon, and it is evidence that the drug has accurately entered the dermal layer.

At Kkeut Korean Medicine Clinic, we always confirm the 'embo' phenomenon with the patient after the procedure.

While typical PN often shows an 'embo' lasting 3-7 days or more, EYE Endran has a low viscosity, so it usually absorbs quickly, often not lasting a full week. The pain is also less than with typical PN, allowing for comfortable treatment even in sensitive areas like around the eyes.

Recommended for those who:

• Are starting to develop fine wrinkles around their eyes.
• Are concerned about bluish dark circles. The bluish tint around the eyes is due to the dermis being too thin, revealing the blood vessels. EYE Endran can subtly increase dermal thickness, thereby alleviating dark circles.
• Experience makeup caking and rough skin texture due to inner dryness.
• Those who find lifting procedures burdensome due to sensitive and thin skin.
• Those who feel that eye cream effects are insufficient.
• Those who have fine lines on their eyelids but have been told by other clinics that the procedure is difficult.
• Those who are concerned about fine lines right next to their eyes.

Procedure Cycle and Duration of Effect

• We recommend 3 sessions at 1-month intervals.
• Afterwards, retouches every 6 months are sufficient to maintain the effect.
• Typically, the duration of effect is 6 months to 1 year.
• Pain is lower than with existing Rejuran, and swelling naturally subsides within 1-3 days.

A Sincere Message from the Head Doctor

Eye area procedures are not simply about 'smoothing wrinkles,' but truly about enhancing the skin's inherent regenerative and restorative power.

One session of Eye Endran can transform your skin more than a whole jar of eye cream.

There are times when skin care that involves applying, wiping, and layering is not enough.

In such cases, you need to nourish the skin from within. Procedures that increase the thickness of the dermal layer are effective for this.

Eye Endran can be the start of that journey.

If you are truly committed to your skin, then the hands performing the procedure must also be genuinely dedicated.

The process of precise injection, meticulous checking, and ensuring patient satisfaction until the very end.

Our medical team at Kkeut Oriental Clinic will be with you throughout that process.